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Logo: Institut für Mehrphasenprozesse/Leibniz Universität Hannover
Logo Leibniz Universität Hannover
Logo: Institut für Mehrphasenprozesse/Leibniz Universität Hannover
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Oleksandr Gryshkov, PhD


Gruppensprecher der AG "Tieftemperaturanwendungen / Kryotechnik"
Institut für Mehrphasenprozesse
Callinstrasse 36
30167 Hannover

Besucheradresse 1

Nienburgerstrasse 1
30167 Hannover

Besucheradresse 2

Niedersächsisches Zentrum für Biomedizintechnik, Implantatforschung und Entwicklung
AG Glasmacher, Room 2020
Stadtfelddamm 34, 30625 Hannover

Telefon:+49(0) 511 762 3822 / 0511 532 1342
Fax:+49(0) 511 762 3031
E-Mail:gryshkovimp.uni-hannover.de

Bild von  Oleksandr Gryshkov, PhD

Projektträger

Wege in die Forschung II: "ArtiBone: Cryopreservation of tissue-engineered bone substitutes" (01.09.2016-28.02.2018) LINK

Forschungsprojekte

  • Verkapselung von Zellen in Alginat-Kapseln
  • Kryokonservierung von TE-Gerüststrukturen und adherenten Zellen
  • Entwicklung von bioaktiven Beschichungen auf bio-SiC, Magnesium und titanium-basierten medizinischen Implantaten

Studium

seit 04/2015 - PostDoc am Institut für Mehrphasenprozesse, Gottfried Wilhelm Leibniz Universität, Hannover, Deutschland

01/2015 - PhD in Biomedical Engineering, Medizinische Hochschulle Hannover und Institut für Mehrphasenprozesse

10/2011 - 03/2015 - Doktorand Institut für Mehrphasenprozesse, Gottfried Wilhelm Leibniz Universität, Hannover, Deutschland

11/2012 - 10/2013 - Fernstudium (Marketing), Kharkiv Staatliche Universität für Lebensmitteltechnologie und Handel, Kharkiv, Ukraine

11/2009 - 10/2012 - Doktorand (Festkörperphysik), Institüt für Halbleiterphysik, Nationale Akademie der Wissenschaften der Ukraine, Kiew, Ukraine

09/2007 - 06/2009 - Master of Sciences (Festkörper Physik, Physikleherer), Nationale Taras-Schewtschenko Universität, Kiew, Ukraine

09/2003 - 06/2007 - Baschelor of Sciences (Physik), Nationale Taras-Schewtschenko Universität, Kiew, Ukraine

Publikationen

Artikel

2017

  • M.Yu. Tymkovych, O.G. Avrunin, V.G. Paliy, M. Filzow, O. Gryshkov et al. Automated method for structural segmentation of nasal airways based on cone beam assisted computed tomography. Photonics Applications in Astronomy, Communications, Industry, and High-Energy Physics Experiments 2017, Edition: Proceedings of SPIE, Chapter: 10445, Editors: Romaniuk Ryszard S., Linczuk Maciej, pp.104453F.
  • V. V. Mutsenko, O. Gryshkov , L. Lauterboeck, et al. Novel chitin scaffolds derived from marine sponge Ianthella basta for tissue engineering approaches based on human mesenchymal stromal cells:Biocompatibility and cryopreservation. Int J Biol Macromol 2017 - accepted
  • A. Chatterjee, D. Saha, H. Niemann, O. Gryshkov, B. Glasmacher, N. Hofmann. Effects of cryopreservation on the epigenetic profile of cells. Cryobiology 2017;74: 1-7 - LINK

2016

  • O. Gryshkov, N.I. Klyui, V.P. Temchenko, et al. Porous biomorphic silicon carbide ceramics coated with hydroxyapatite as prospective materials for bone implants. Mater Sci Eng C 2016;68: 143-152 - LINK
  • L. Lauterboeck, O. Gryshkov, N. Hofmann, et al. Importance of controlled ice formation for efficient biobanking. Refrigeration Science and Technology 2016;F126957: 84-90. doi: 10.18462/iir.cals.2016.0007

2015

  • A. Repanas, W.F. Wolkers, O. Gryshkov, M. Müller, B. Glasmacher. PCL/PEG electrospun fibers as drug carriers for the controlled delivery of dipyridamole. Journal of In Silico & In Vitro Pharmacology 2015;1(1:2) in press - LINK
  • A. Repanas, W.F. Wolkers, O. Gryshkov, et al. Coaxial electrospinning as a process to engineer biodegradable polymeric scaffolds as drug delivery systems for anti-inflammatory and anti-thrombotic pharmaceutical agents. Clinical & Experimental Pharmacology 2015;5: 192, DOI:10.4172/2161-1459.1000192 - LINK
  • O. Gryshkov, N. Hofmann, L. Lauterboeck, T. Mueller, D. Pogozhykh, B. Glasmacher. Multipotent Stromal Cells Derived from Common Marmoset Callithrix Jacchus within Alginate 3D Environment: Effect of Cryopreservation Procedures. Cryobiology 2015:71(1): 103-111 - LINK

 2014

  • O. Gryshkov,  D. Pogozhykh, N. Hofmann, O. Pogozhykh, T. Mueller, B. Glasmacher. Encapsulating Non-Human Primate Multipotent Stromal Cells in Alginate via High Voltage for Cell-Based Therapies and Cryopreservation. PLoS One 2014;9(9): e107911 - LINK
  • O. Gryshkov, D. Pogozhykh, N. Hofmann, H. Zernetsch, B. Glasmacher. Process engineering of high voltage alginate encapsulation of mesenchymal stem cells. Mater Sci Eng C 2014;36: 77-83 - LINK

2013

  • M.I. Klyui, V.P. Temchenko, O.P. Gryshkov, et al. Bio-SiC ceramics coated with hydroxyapatite using gas-detonation deposition: An alternative to titanium-based medical implants. Functional materials 2013;20(2): 163-171 - LINK

2012

  • M.I. Klyui, V.P. Temchenko, A.V. Makarov, O.P. Gryshkov, V.O. Yukhymchuk. Properties of micro- and nano-structured silicon layers produced by gas-detonation deposition. Technical Electrodynamics 2012, Thematic Issue: 198-203

2011

  • N.I. Klyui, V.P. Temchenko, A.P. Gryshkov, et al. Properties of the hydroxyapatite coatings obtained by gas-detonation deposition onto titanium substrates. Functional Materials 2011;18(3): 285-292 - LINK

Abstracts

2017

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2016

  • V.V. Mutsenko, O. Gryshkov, S. Knaack, et al. Cryopreservation of biomimetic bone matrix with non-human primate mesenchymal stromal cells. Cryobiology 2016;73(3): 433.
  • V.V. Mutsenko, O.P. Gryshkov, Yu.A. Petrenko, et al. The impact of sucrose pretreatment on survival of mesenchymal stromal cells, cryopreserved in suspension and adherent state. Cryobiology 2016;73(3): 402.
  • S. Suresh, O. Gryshkov, B. Glasmacher. Controlled infiltration of cells into spherical polymeric scaffolds. Int J Artif Organs 2016; 39(7): 373.
  • B. Glasmacher, L. Lauterboeck, D. Saha, A. Chatterjee, S. Suresh, T. Rittinghaus, O. Gryshkov. Cell and tissue encapsulation in alginate for safe cryopreservation. Cryobiology 2016;73(3): 407.
  • O. Gryshkov, N. Klyui, V. Temchenko, B. Glasmacher. Deposition of bioactive and bioinert ceramic coatings on magnesium using detonation. Biomed Tech 2016;61: 198.
  • S. Suresh, O. Gryshkov, B. Glasmacher. Development of Volvox spheres for the co-culture of cardiovascular cells for tissue engineering. Biomed Tech 2016;61: 89.
  • F. AL Halabi, A. Repanas, M. Müller, O. Gryshkov, B. Glasmacher. Piezoelectric effect of PFDV and PVDF-TrFE scaffolds. Biomed Tech 2016;61: 89.

2015

  • O. Gryshkov, N. Klyui, V. Temchenko, et al. Porous bio-SiC ceramics from wood: approaching new medical implants. World Congress on Medical Physics and Biomedical Engineering – IUPESM 2015, 7-12 June 2015, Toronto, Canada, pp. 283-284.
  • O. Gryshkov, H. Zernetsch, N. Hofmann, B. Glasmacher. Alginate encapsulation: a solution for controlled infiltration of cells within artificial fiber constructs. World Congress on Medical Physics and Biomedical Engineering – IUPESM 2015, 7-12 June 2015, Toronto, Canada, pp. 205.
  • O. Gryshkov, L. Lauterboeck, N. Hofmann, B. Glasmacher. Temperature of ice formation affects integrity of alginate 3D constructs after cryopreservation. World Congress on Medical Physics and Biomedical Engineering – IUPESM 2015, 7-12 June 2015, Toronto, Canada, pp. 535.
  • V.M. Kapralova, D.D. Karov, V.V. Loboda, O. Gryshkov, B. Glasmacher. Study of mechanical and degradation behavior of new copolymers for medical implants. 11th German-Russian Conference on Biomedical Engineering, 17-19 June 2015, Aachen, Germany, pp. 103-105.
  • O. Gryshkov, N. Klyui, V. Temchenko, V. Dubok, V. Kyselyov, A. Belyaev, B. Glasmacher. Deposition of bioactive coatings on porous bio-SiC ceramics derived from wood. 11th German-Russian Conference on Biomedical Engineering, 17-19 June 2015, Aachen, Germany, pp. 107-109.
  • M. Tymkovych, O. Gryshkov, O. Avrunin, A. Kern, B. Glasmacher. An approach to visualize alginate 3D structures with encapsulated cells for cell-based therapies and cryopreservation. 11th German-Russian Conference on Biomedical Engineering, 17-19 June 2015, Aachen, Germany, pp. 13-15.
  • O. Gryshkov, M. Tymkovych, O. Avrunin, et al. Visualization of alginate beads with encapsulated cells for cryopreservation and cell-based therapies. International Journal of Artificial Organs 2015;38(7): 408.

2014

  • O. Gryshkov, D. Pogozhykh, N. Hofmann, F. AL Halabi, T. Mueller, B. Glasmacher. High voltage alginate encapsulation of stem cells for transplantation and cryopreservation. Int J Artif Organs 2014;37(8): 643 - LINK
  • O. Gryshkov, D. Pogozhykh, N. Hofmann, T. Mueller, B. Glasmacher. Cryopreservation of monkey mesenchymal stem cells inside alginate 3D microspheres after a high voltage encapsulation. Cryobiology 2014;69(3): 514 - LINK
  • B. Glasmacher, O. Gryshkov, L. Lauterboeck, D. Pogozhykh, T. Mueller, N. Hofmann. Cryopreservation of alginate encapsulated monkey stem cells under controlled induced nucleation. Cryobiology 2014;69(1): 186 - LINK

2013

  • O. Gryshkov, D. Pogozhykh, N. Hofmann, T. Mueller, B. Glasmacher. Cryopreservation of stem cells inside alginate 3D constructs after high-voltage encapsulation. Cryobiology 2013;67(3): 429 - LINK
  • O. Gryshkov, D. Pogozhykh, N. Hofmann, B. Glasmacher. Cell encapsulation into alginate micro-capsules provides living cells with a mild environment during cryopreservation. Cryobiology 2013;66(3): 352 - LINK
  • H. Zernetsch, A. Repanas, A. Gryshkov, F. Al Halabi, T. Rittinghaus et al. Solving Biocompatibility Layer by Layer: Designing Scaffolds for Tissues. Biomedizinische Technik. Biomedical engineering 2013, doi: 10.1515/bmt-2013-4065 - LINK
  • O. Gryshkov, N. Hofmann, B. Glasmacher. Electropsraying as a promissing technique for cell encapsulation in semi-permeable micro-capsules for immunoisolation. Cryo Letters 2013;34(2): 186 - LINK

2012

  • O. Gryshkov, N. Hofmann, B. Glasmacher. Cell encapsulation in semi-permeable alginate micro-capsules using high-voltage processes. Problems of Cryobiology 2012;22(3): 346
  • O. Gryshkov, N. Hofmann, B. Glasmacher. Alginate encapsulation technology improves survival of living cells post-cryopreservation. Problems of Cryobiology 2012;22(3): 345

Vorträge

2015

  • O. Gryshkov, N. Hofmann, D. Wirth, T. Mueller, B. Glasmacher. Multistructural alginate encapsulation of drugs, cells and cellular therapeutics. ACHEMA 2015, 19 June 2015, Frankfurt, Germany - Vortrag
  • M. Tymkovych, O. Gryshkov, O. Avrunin, et al. An approach to visualize alginate 3D structures with encapsulated cells for cell-based therapies and cryopreservation. 11th German-Russian Conference on Biomedical Engineering, 17-19 June 2015, Aachen, Germany, p. 13-15 - Poster.
  • O. Gryshkov, N. Klyui, V. Temchenko, et al. Deposition of bioactive coatings on porous bio-SiC ceramics derived from wood. 11th German-Russian Conference on Biomedical Engineering, 17-19 June 2015, Aachen, Germany, p. 107-109 - Poster.

2014

  • O. Gryshkov, D. Pogozhykh, N. Hofmann, T. Mueller, B. Glasmacher. Cryopreservation of monkey mesenchymal stem cells inside alginate 3D microspheres after a high voltage encapsulation. 2014 World Forum on Biology – Joint Meeting of the Society for In Vitro Biology and the Society for Cryobiology, 02.01.2014, Savannah, Georgia - Vortrag (Peter L. Steponkus Crystal Award Presentations).

2013

  •  O. Gryshkov, N. Klyui, V. Temchenko, F. Evertz, V. Dubok, et al. Bioactive and bioinert coatings onto magnesium substrates obtained by gas-detonation deposition: surface morphology studies. 1st Russian-German Conference on Biomedical Engineering, October 23rd – 26th, 2013, Hannover, Germany, p. 5 - Vortrag
  • O. Gryshkov, H. Zernetsch, N. Hofmann, D. Pogozhykh, B. Glasmacher. Engineering of artificial perfusion membrane for biomedical applications. 1st Russian-German Conference on Biomedical Engineering, October 23rd – 26th, 2013, Hannover, Germany, p. 85 - Poster
  • O. Gryshkov, D. Pogozhykh, T. Mueller, N. Hofmann, B. Glasmacher. Encapsulation of mesenchymal stem cells into alginate 3D constructs helps to overcome challenges during cryopreservation. The 3rd International Congress on Controversies in cryopreservation of stem cells, reproductive cells, tissue and organs (Cryo), Berlin, Germany, March 21st-23rd 2013 - Poster

2010

  • N.I. Klyui, V.P. Temchenko, O.P. Gryshkov et al. Characteristics of the hydroxyapatite gas-detonation coatings, deposited onto titanium substrates. Ukrainian-German Symposium on Physics and Chemistry of Nanostructures and on Nanobitechnology. Beregove, The Crimea, Ukraine, 6th-10th September, 2010, p. 214 - Poster.

Preise

Presse

 

  • O. Gryshkov. F. Evertz, B. Glasmacher. “Mit 1200 m/s ans Ziel: Neuartige bioaktive Beschichtungen für medizinische Anwendungen“ in „Neu Materialien“, Unimagazin,  Leibniz Universitaet Hannover, 1/2, 2014, p. 56-59 - LINK
  • O. Gryshkov. “Arbeiten in REBIRTH/Working in REBIRTH”.  REBIRTH Newsletter, January 2013, p. 24 - LINK

 

Kooperationen

Cooperation with Ukraine

Externe Links

Weitere Aktivitäten

  • seit 2015 Gruppenspreche der Forschungsgruppe Tieftemperatur Anwendungen / Kryotechnik
  • Betreuung der Bildgebungtutorium
  • Betreuung des Kooperationsprojektes Frozen Life mit der St. Ursula-Schule Hannover